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Cyclophosphamide is a cancer medication that interferes with the growth and spread of cancer cells in the body. Cyclophosphamide is used to treat several types of cancer. Cyclophosphamide is also used to treat certain cases of nephrotic syndrome (kidney disease) in children.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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Cyclophosphamide is used to treat cancer of the ovaries, breast, blood and lymph system, and nerves (mainly in children). Cyclophosphamide is also used for retinoblastoma (a type of eye cancer mainly in children), multiple myeloma (cancer in the bone marrow), and mycosis fungoides (tumors on the skin). It belongs to the group of cancer medicines called alkylating agents.

Cyclophosphamide is also used for some kinds of kidney disease.

Cyclophosphamide interferes with the growth of cancer cells, which are then destroyed by the body. Since the growth of normal body cells may also be affected by cyclophosphamide, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects, like hair loss, may not be serious but may cause concern. Some effects may not occur for months or years after the medicine is used.

Before you begin treatment with cyclophosphamide, you and your doctor should talk about the benefits of this medicine as well as the risks of using it.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Capsule
  • Powder for Solution
  • Tablet

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Four weeks later, motoneurons innervating the vastus lateralis muscle of the quadriceps were labeled with cholera toxin-conjugated horseradish peroxidase, and dendritic arbors were reconstructed in three dimensions. These MS-derived carbons show promising performances towards electrocatalysis and capacitive energy storage.

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Patient 5 had dystonic posturing of the right upper extremity with tremor of the left upper extremity. Greater public health expenditure is urgently needed to implement feasible, effective alternatives in terms of access and health care. However, the detailed investigation of nanoscale structures is still challenging. Successful anesthesia can be performed in critically ill renal transplant recipients. Compounds from leaf extracts of neem, were also screened to identify the natural drugs without side effects.

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Within the wide-ranging gamut of factors that comprise gene-environment interactions postulated to underlie schizophrenia, the crosstalk between environmental factors and feto-maternal immune components has been put forth as one of the important mechanisms that increase the risk towards schizophrenia in the offspring. Our analysis reveals that the transactivation domain and not the SET domain is important for the S-phase function of MLL. Our findings underscore the value of HIV outreach programmes which combine ART, peer support and economic empowerment to alleviate HIV stigma. In the current study we define the cytoplasmic conditions necessary for this modification of 8-cell and 16-cell stage nuclei in hybrids obtained by fusion with metaphase II arrested oocytes, oocytes at various time points after parthenogenetic activation, naturally fertilized eggs (zygotes) and interphase 2-cell embryo blastomeres. High affinity binding of TAR RNA by the human immunodeficiency virus type-1 tat protein requires base-pairs in the RNA stem and amino acid residues flanking the basic region.

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Modification of citrus and apple pectin by power ultrasound: Effects of acid and enzymatic treatment. The qualitative and quantitative evaluation on the MIT intrinsic dataset indicated that the quality of intrinsic image decomposition was improved in comparison with previous methods.

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Our data lend further support to the clinical validity of Doppler umbilical velocimetry in identifying fetal acidosis or compromise. After brushing, rinsing for one minute with the toothpaste slurry and a sip of water possibly increases the effectiveness of the toothpaste. Chemokines, a family of soluble and membrane-bound cytokines, play an essential role in mediating neuron-microglia crosstalk in the developing and mature brain. All factors except seniority were found to affect the presence of musculoskeletal discomfort in some area of the body. Measuring microangiopathy abnormalities in systemic sclerosis patients: the role of capillaroscopy-based scoring models.

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The full Elsevier Policy on Article Withdrawal can be found at This study confirmed significant associations between addictive use of the Internet at the age of 15 and heavy drinking and cigarette smoking at the age of 20.

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Although they are a little smaller and probably aggregate less with hyaluronic acid, these populations correspond in size and composition to two similar populations detected in situ in healthy adult human articular cartilage. Although some causes of male subfertility are treatable, treatment of idiopathic male factor subfertility remains empirical. Addressed training regarding CPR/DNAR orders is necessary to improve the CPR/DNAR decision process used by physicians. In conclusion, the ability to detect the gas signal of laser absorption spectroscopy shows the potential for the medical application of assessing the human femoral head in vivo.

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Tetrakis-acridinyl peptide: distance dependence of photoinduced electron transfer in deoxyribonucleic acid assemblies. Using novel methods to image nutrient translocation, its mycelium has been modeled as a highly responsive resource-supply network. Of 38 cattle with upward fixation of the patella, 34 were treated surgically. The efficacy of automatic suspension of insulin delivery in induced hypoglycemia among subjects with type 1 diabetes was evaluated. We also review the literature on links between alcohol consumption and azoospermia.

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Despite the critical role of OspF, the mechanism by which it localizes in the nucleus has remained to be elucidated. This information should be used to develop public prevention strategies and to educate the community about the risk of TBI especially the risk of falls in the ageing population. Interferon-gamma arrests proliferation and causes apoptosis in stromal cell/interleukin-7-dependent normal murine pre-B cell lines and clones in vitro, but does not induce differentiation to surface immunoglobulin-positive B cells.

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Effectiveness of Early Antiviral Therapy in Disseminated Neonatal Herpes Simplex Virus 2 (HSV-2) with Fulminant Hepatic Failure. The indications are that we are studying the formation of a transition intermediate which is destabilized by the denaturant and which resembles the A intermediate of the framework or molten globule models for protein folding. To evaluate the quantitative analysis by real-time elastosonography in the differential diagnosis of obstructive azoospermia (OA) and non-obstructive azoospermia (NOA).

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However, little is known about dietary TAC among the Korean population. The levels of Cd, Co, and Ni in carcinoma and healthy control tissues was determined by inductively coupled plasma optical emission spectrometry (ICP - OES) using sequential spectrometer.

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Toxicity and tissue accumulation of copper in chicks fed casein and soy-based diets. Socioeconomic disparities in the operative management of peptic ulcer disease. In vertebrates, the orthologous ULK1 kinase complex contains the Ser/Thr kinase ULK1 and the accessory proteins ATG13, RB1CC1, and ATG101. Results for barley and malt show good correlation with those obtained by flow-injection analysis using calcofluor. A total of 579 male patients diagnosed with APD were examined in a military hospital setting.

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The severity of obstructive sleep apnea is associated with increased risk of death, and risk stratification based on OSA severity is relevant even in the diseased cardiac patient. Community based preventive programmes should be Most patients experienced improvement with therapy, including a majority with 3,4-DAP. A significant association was found between involvement in group-oriented programs and recognition of risk factors unique to the profession. A Matlab algorithm enabled fast automated counting of flock fibres on the images.

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Such digital displays and reports may not be optimum for estimating the graded levels of intervention required for specific physiologic problems. Treatment is now given with multiple-energy linear accelerators, CT-based simulation, 3-dimensional beam modulation for much greater dose homogeneity, on-board imaging for greater daily accuracy, and various techniques to reduce cardiac dose. The presence of a sigma factor on the surface playing a secondary role, probably mediating host-pathogen interaction, suggests that LIC11122 is a moonlight protein candidate. Presensitization to human leukocyte antigen (HLA) tends to decrease renal graft survival.

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This deficit was found to be not only modality-specific but music-specific as well. The grain hardness (Ha) locus on chromosome 5D was associated with particle size index and flour extraction and a region on chromosome 3B was associated with grain width, thickness, thousand grain weight and yield. Previous research indicates that 2 classes of RVM neuron, the on- and off-cells, facilitate and inhibit nociception, respectively. If desired, triggers for beginning these conversations could be provided through public information and school education, which would also contribute to health literacy on this subject.

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Complete dissection was defined as when the PPICA could be visualized. GAGs are ubiquitous constituents of connective tissue, cartilage, and the extracellular matrix, where they have key functions in many important biological processes. Chronic refractory osteomyelitis as a part of synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome: a diagnostic challenge.

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L-glycerate, but not acetyl, groups interfere with the intermolecular association of native gellan molecules and are thus responsible for its weak and rubbery gels. This project demonstrated the successful implementation of HPV vaccination among learners (ages 9 - 12 years) using school health teams. Besides, the primary somatosensory cortex (S1) is thought to play a pivotal role in the sensori-discriminative aspects of pain perception but the analgesic effect of cTBS applied over S1 remains controversial.

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In this article, the authors examine the options available to repair small soft tissue nasal defects and the appropriate situations in which each method is best suited. Hydroxylation of 6alpha-methyl-4-pregnene-21-ol-3,20-dione with Mucor griseo-cyanys. Elonza, a generic product of sildenafil, was an effective and well-tolerated treatment for ED in Thai men.

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Although distribution of free reflective vests led to a statistically significant increase in vest usage, the absolute increase was modest. Nursing of a patient with amyotrophic lateral sclerosis--attempts at assistance at meal time and communication Intramammary metastatic melanoma of unknown primary origin in a 58-year old patient: a case report. This case demonstrates the similarities between the perilous diagnosis of stroke and the more routine diagnosis of migraine. First, it aims to test the effect of reward stability on justice evaluations.

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Restricted gene flow within and between rapidly diverging Neotropical plant species. In the present study, we separately imputed datasets of the Escherichia coli S.O.S. We found that Primo-vessels generated two types of action potential pulses that differed from those of smooth muscle: (1) Type I pulse had rapid depolarizing and repolarizing phases, and (2) Type II pulse had a rapid depolarizing phase and a gradually slowing repolarizing phase. This review contributed to the evidence base for the revised 2013 WHO guidelines on antiretroviral therapy, which recommend that efavirenz can be included as part of first-line therapy in adults regardless of sex, and that it can be used throughout pregnancy, including during the first trimester.

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Calcium deficiency enhances cadmium accumulation in the central nervous system. Interacting impacts of invasive plants and invasive toads on native lizards.

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The relationship of scope of practice (predominantly adult, versus predominantly pediatric) with the outcomes of brain tumor surgery in children remains uncertain. Urine neutrophil gelatinase-associated lipocalin (NGAL), part of an acute response to the release of tissue iron from cells, is an early biomarker and a predictor of AKI in a variety of clinical settings. To assess the safety and efficacy of memantine, an uncompetitive antagonist of the N-methyl-D-aspartate receptor as treatment of HIV-associated cognitive impairment.

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A retrospective review was performed for all robotic surgeries by pediatric urologists at a single pediatric institution, from the start of the robotic surgery program in February 2009 through February 2013. Video-assisted thoracoscopic surgery (VATS) right upper lobectomy was performed for the right upper lobe tumor, which was histopathologically confirmed to be metastatic choroidal melanoma. Furrow regression was observed in Aurora B- and 2P-MRLC-inhibited cells but not in 1P-MRLC-perturbed dividing cells.

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Unplanned complex suicide by self-strangulation associated with multiple sharp force injuries: a case report. One consequence of the shifting economic health care landscape is the growing trend of physician employment and practice acquisition by hospitals.

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The genomes of DNA-containing cell organelles (mitochondria, chloroplasts) can be laterally transmitted between organisms, a process known as organelle capture. tuberculosis PhoP plays an essential role in the expanded regulatory capabilities of this important regulator. Temperature and pressure dependence of the rate coefficient for the reaction between ClO and CH3O2 in the gas-phase. In present study, the acetylated norsol antibiotics and birth derivatives of low-molecular-weight polysaccharide (LEP) was prepared with the method of response surface quadratic model. Of 60 neurones studied, 44 responded to prolonged (greater than 10 sec) stimuli that were well within the noxious range.

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Intestinal obstruction caused by an incarcerated diaphragmatic hernia after an Ivor-Lewis procedure. Three cases of acute dorsal avulsion fracture of the scaphoid are presented. Data on the risk of hepatocellular carcinoma in interferon-treated patients with chronic hepatitis C participating in placebo-controlled trials of interferon have been published after 3 to 9 years of follow-up. Role of complex organic arsenicals in food in urinary tract infection treatment levofloxacin eye aggregate exposure to arsenic.

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Males are more affected than females, an effect which is directly related to smoking. To systematically review qualitative research on PCC for women with pre-existing diabetes mellitus of childbearing age, identify facilitators of and barriers to uptake of PCC and establish themes and gaps in knowledge. Negative pressure wound therapy incorporating early exercise therapy in hand surgery: bag-type negative pressure wound therapy. Individuals rely on the perception of pain to avoid injury, to signal disease, and to warn about tissue inflammation and damage. The granular medium is then visualized by losar bp medicine exciting, layer by layer, the fluorescent dye in the fluid phase.

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The study cohort included 61 patients with renal cell carcinoma extending into the renal vein or inferior vena cava that underwent operations between 1993 and 2012. Morphine did not influence tumour development when given before the onset of tumour appearance, but significantly promoted progression of established tumours, and reduced survival. Progressive vasodegeneration in microvascular beds is the major underlying factor in initiation and progression of diabetic complications. Contraception-induced mood changes have been identified since the 1960s. A somewhat higher sensitivity veclam 500 mg claritromicina 250 for the diagnosis of bone metastases was found for urinary NTx (N-terminal cross-linked telopeptide of type I collagen) and serum ICTP in solid tumor patients, serum TRAcP-5b (Tartrate-resistant acid phosphatase type 5b) in patients with breast cancer and serum BSAP, PINP and OPG in prostate cancer patients.

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The geographic region where this envenomation occurred has a documented population of Southern Pacific rattlesnakes with Mojave toxin in their venom. The anaerobic performance of the children with CP was lower than that of peers with typical development. To reach these conclusions, a specific methodology using ImageJ iv augmentin in renal impairment symptoms free software was developed to enable characterization of the fast three-dimensional movement of single-pRBCs. The average hair Hg content (1.504 microg x g(-1)) in male traffic polices is higher than that (1.176 microg x g(-1)) of female traffic polices,while the average hair Pb content (2.852 microg x g(-1) in male traffic polices lower than that (2. These investigations will form the foundation for further improvements in our ability to care for patients with these tumors and may offer clinical insights into a wide range of other tumors.

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