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Dose-comparison study of the combination of Ezetimibe and simvastatin (Vytorin) versus atorvastatin in patients with hypercholesterolemia: the Vytorin Versus Atorvastatin (VYVA) study. It is well tolerated but hepatic toxicity has been reported when Ezetimibe is used in conjunction with a statin medication.

Other names for this medication:
Ezetimibe, Zetia, Ezedoc, Ezetimiba, Ezetrol, Zient,

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Ezetimibe is used together with lifestyle changes (diet, weight-loss, exercise) to reduce the amount of cholesterol (a fat-like substance) and other fatty substances in the blood. It may be used alone or in combination with an HMG-CoA reductase inhibitor (statin). Ezetimibe is in a class of medications called cholesterol-lowering medications. It works by preventing the absorption of cholesterol in the intestine.

Buildup of cholesterol and fats along the walls of the blood vessels (a process known as atherosclerosis) decreases blood flow, which decreases the oxygen supply to the heart, brain, and other parts of the body. Lowering blood levels of cholesterol and fats may help reduce this buildup and may decrease your chances of developing heart conditions such as angina (chest pain), strokes, and heart attacks. Results of a clinical study that compared people who took ezetimibe and simvastatin with people who took simvastatin alone found that although the group of people taking ezetimibe and simvastatin had lower amounts of cholesterol in the blood, there was no difference between the two groups in the amount of cholesterol and fat buildup on the insides of the blood vessels in the neck. It is not currently understood why the additional lowering of cholesterol levels in the blood did not lead to a greater decrease in cholesterol and fat buildup along the walls of the blood vessels in people taking ezetimibe and simvastatin. Further studies are underway to compare treatment with ezetimibe and simvastatin to treatment with simvastatin alone to see if there is a difference in the risk of developing heart disease. Talk to your doctor if you have questions about the risks and benefits of treating increased amounts of cholesterol in your blood with ezetimibe and other medications.

In addition to taking a cholesterol-lowering medication, making certain changes in your daily habits can also lower your blood cholesterol levels. You should eat a diet that is low in saturated fat and cholesterol (see SPECIAL DIETARY); exercise 30 minutes on most, if not all, days; and lose weight if you are overweight.

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Complete Genomic Sequences of an H3N8 Equine Influenza Virus Strain Isolated in China. Indeed, the porcine membrane was well-integrated into the host tissue, with no noticeable foreign body reaction at three months post-surgery. The formulation was investigated systematically with the dissolution tests as predominant method. Depletion of monocytes marginated within the lung microvasculature, achieved by pretreating mice with i.v.

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The Fe-heme structure of met-indoleamine 2,3-dioxygenase-2 determined by X-ray absorption fine structure. Marsupials from Oceania were negatively affected by habitat disturbance, whereas there was no effect for those from South America. All trials collected covariates and outcomes data at baseline and follow-ups. The successful supportive management of an acute combined strychnine and aconitine poisoning is described.

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Effects of motor unit losses on strength in older men and women. The cellular yes (c-yes) gene is a member of the class of proto-oncogenes that encode non-receptor tyrosine protein kinases. On the other hand, pegylated nanoliposomal carrier showed higher loading efficiency and less release compared with nanoliposomal carrier which verifies effect of PEG on improvement of stability and efficiency. Measures of affective temperament-types were independently and more strongly associated with lifetime suicide attempt than was diagnosis of a major affective disorder.

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Posterior teeth occlusion and dysphagia risk in older nursing home residents: a cross-sectional observational study. Immunohistochemical study was performed in appropriate blocks for using MLH-1, MSH-2, MSH-6, and PMS-2. Trajectories of Sleep Disturbance Severity in HIV-Infected and Uninfected Veterans. Glucagon-like peptide-1 receptor (Glp-1R) agonists are hypoglycemic agents with pleiotropic vascular protective and anti-inflammatory effects.

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Parents of older at-risk youth: a retention challenge for preventive intervention. Alcohol and nicotine dependence are serious public health problems worldwide.

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For genotype 1b Hepatitis C virus (HCV), the RNA-dependent RNA polymerase (RdRp) subunit of the replicase, NS5B, has been reported to interact with the HCV Core protein to decrease RNA synthesis (Kang et al., 2009). Methylation-Sensitive Melt Curve Analysis of the Reprimo Gene Methylation in Gastric Cancer. Impact of a prostate multidisciplinary clinic program on patient treatment decisions and on adherence to NCCN guidelines: the William Beaumont Hospital experience. During face matching, there was a significant correlation in the right hemisphere between an extrastriate occipital region that was equally activated during both the face matching and dot-location matching tasks and a region in inferior occipitotemporal cortex that 2mg lorazepam high effects was activated more during the face matching task. A polymorbid patient with complete infection of the aortobifemoral prosthetic graft, with abscess in the groin and bilateral occlusion of the superficial femoral artery was treated by complete graft explantation and implantation of extra-anatomical axillobipopliteal bypass.

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Developmental dysphasia and epileptiform EEG activity in children The previous hot thyroid areas manifested hypofunction at technetium-99 m-pertechnetate scintiscan, and the surrounding parenchyma returned to normal function in all but the 3 cases with still suppressed TSH. A questionnaire was used to obtain the following information: demographic information, religion, the rate of use of TM, reasons why guardians chose to use TM, the diagnoses made by the TH, treatment offered, and the type of payment requested, based on the accounts of patient caregivers. The lansoprazole 30 mg cap kinetics of the collagen collection showed a positive correlation with the kinetics of DNA synthesis, 16 h later.

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